تفاعل #61524

معادلة التفاعل

5-Thiophen-2-yl-2H-pyrazole-3-carboxylic acid ethyl ester

2-Bromo-N-(4-chloro-phenyl)-acetamide

4-Cyano-2H-pyrazole-3-carboxylic acid ethyl ester

2-Bromo-N-(5-chloro-pyridin-2-yl)-acetamide

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title compound

2-[(4-Chloro-phenylcarbamoyl)-methyl]-4-cyano-2H-pyrazole-3-carboxylic acid (1-isopropyl -piperidin-4-yl)-amide

ظروف التفاعل

الإجراء التجريبي

The title compound was prepared analogously to example 1 with the difference that 2-Bromo-N-(4-chloro-phenyl)-acetamide and 4-Cyano-2H-pyrazole-3-carboxylic acid ethyl ester were used instead of 2-Bromo-N-(5-chloro-pyridin-2-yl)-acetamide and 5-Thiophen-2-yl-2H-pyrazole-3-carboxylic acid ethyl ester in the alkylation step. MS (ESI+): m/e=429, chloro pattern.

المصدر