تفاعل #61432

معادلة التفاعل

2-isopropoxy-5-methanesulfonyl-benzoic acid

2-Piperazin-1-yl-benzothiazole-4-carboxylic acid methyl ester hydrochloride

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title compound

2-[4-(2-Isopropoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-benzothiazole-4-carboxylic acid methyl ester

المذيبات

tetrahydrofuran

ظروف التفاعل

المعالجة

1. 1
   أخرىThe crude material was purified by chromatography (SiO2, heptane/ethyl acetate)
2. 2
   أخرىthe residue was then triturated in ether

الإجراء التجريبي

Prepared in analogy to example 1.1 b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.2) and 2-Piperazin-1-yl-benzothiazole-4-carboxylic acid methyl ester hydrochloride in tetrahydrofuran. The crude material was purified by chromatography (SiO2, heptane/ethyl acetate), and the residue was then triturated in ether to yield the title compound as a white solid.

المصدر