تفاعل #6100

ord-0e3bf4991a3f466d9c41ae0105fc4554

معادلة التفاعل

[K+].[OH-]
potassium hydroxide
N#Cc1ccccc1O
2-hydroxybenzonitrile
CN(C)C(=S)Cl
dimethylthiocarbamoyl chloride
CN(C)C(=S)Oc1ccccc1C#N
expected product
المردود 94.0%
CN(C)C(=S)Oc1ccccc1C#N
O-2-cyanophenyl dimethylthiocarbamate
المردود 94.0%

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

If the procedure described in Preparation XVI is followed starting from 15 g (126.10-3 mol) of 2-hydroxybenzonitrile, 17.9 g (145.10-3 mol) of dimethylthiocarbamoyl chloride and 7.4 g (126.10-3 mol) of potassium hydroxide, 24.1 g (yield: 94%) of the expected product are obtained.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05246961uspto-grants-1993_09