تفاعل #609528

معادلة التفاعل

Sodium carboxylate

sodium 2-trifluoromethylbicyclo[2,2,1]hepta-5-ene-2-carboxylate

triphenylsulfonium chloride

→

objective material

المردود 40.0%

triphenylsulfonium 2-trifluoromethylbicyclo[2,2,1]hepta-5-ene-2-carboxylate

المردود 40.0%

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   أخرىThe organic layer was separated
2. 2
   استخلاصthe aqueous layer was extracted with CH2Cl2
3. 3
   غسيلthe combined organic layers were washed three times with H2O
4. 4
   workup.DISTILLATIONThe solvent was distilled off under reduced pressure

الإجراء التجريبي

Sodium carboxylate (21) obtained in (Synthesis Example 1-1-2) was dissolved in 20 g of methylene chloride, 40 g of an aqueous solution of triphenylsulfonium chloride (22) was added to the solution and the resulting mixture was stirred for 30 minutes. The organic layer was separated, the aqueous layer was extracted with CH2Cl2, and the combined organic layers were washed three times with H2O. The solvent was distilled off under reduced pressure to obtain 4.6 g of the objective material, onium salt (Q-1) (Yield: 40%).

المصدر