تفاعل #60771

ord-7b618d09fbb341909742f5d50cbd899a

معادلة التفاعل

[N-]=C=O
isocyanate
CNc1ccc(N2CN=c3sccc3=C2N)cc1
4-amino-3-(4-(methylamino)phenyl)-thieno[2,3-d]pyrimidine
CCc1ccccc1N=C=O
2-ethyl-phenyl isocyanate
CCc1cccc(NC(=O)N(C)c2ccc(N3CN=c4sccc4=C3N)cc2)c1
4-Amino-3-(4-((3-ethylphenyl)aminocarbonyl(N-methylamino))-phenyl)thieno[2,3-d]pyrimidine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe compound was prepared

الإجراء التجريبي

The compound was prepared following the procedure described in Example 429, substituting 4-amino-3-(4-(methylamino)phenyl)-thieno[2,3-d]pyrimidine as the amine and using 2-ethyl-phenyl isocyanate as the isocyanate of choice. MH+=404.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07427623B2uspto-grants-2008_09