تفاعل #60762

ord-a8e1eeb6f84c4593a536d2c6952de70b

معادلة التفاعل

O=C=Nc1ccc2c(c1)CCC2
5-indanyl isocyanate
[N-]=C=O
isocyanate
NC1=c2ccoc2=NCN1c1cccc(N)c1
4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine
NC1=c2ccoc2=NCN1c1cccc(NC(=O)Nc2ccc3c(c2)CCC3)c1
4-Amino-3-(3-((5-indanyl)aminocarbonylamino)phenyl)furo[2,3-d]pyrimidine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe compound was prepared

الإجراء التجريبي

The compound was prepared following the procedure described in Example 232(b), using 5-indanyl isocyanate as the isocyanate of choice, and 4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine (10) as the diamine of choice. MS(ES) m/e 386 [M+H]+.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07427623B2uspto-grants-2008_09