تفاعل #60761

ord-d0699c594224466da4a32d77eb82c0a8

معادلة التفاعل

O=C=NS(=O)(=O)Cl
chlorosulfonyl isocyanate
[N-]=C=O
isocyanate
NC1=c2ccoc2=NCN1c1cccc(N)c1
4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine
NC(=O)Nc1cccc(N2CN=c3occc3=C2N)c1
4-Amino-3-(3-(aminocarbonylamino)phenyl)furo[2,3-d]pyrimidine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe compound was prepared

الإجراء التجريبي

The compound was prepared following the procedure described in Example 232(b), using chlorosulfonyl isocyanate as the isocyanate of choice, and 4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine (10) as the diamine of choice. MS(ES) m/e 270 [M+H]+.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07427623B2uspto-grants-2008_09