تفاعل #6072

معادلة التفاعل

maleic anhydride

phenyl vinyl sulfide

ethylaluminum dichloride

→

title compound

المردود 90.7%

2,4-dioxo-6-phenylthio-3-oxabicyclo[3.2.0]heptane

المردود 90.7%

المذيبات

1,2-dichloroethane

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   غسيلThe methylene chloride solution was washed three times with saturated aqueous ammonium chloride solution
2. 2
   تجفيفonce with brine, dried over anhydrous sodium sulfate
3. 3
   تركيزconcentrated

الإجراء التجريبي

To a solution of maleic anhydride (0.39 g, 4 mmol) and phenyl vinyl sulfide (0.52, 4 mmol) in 17 mL of 1,2-dichloroethane under nitrogen, was added 2 mL (0.5 equiv) of ethylaluminum dichloride. The resultant solution was stirred at ambient temperature for 0.5 h and then diluted with 75 mL of methylene chloride. The methylene chloride solution was washed three times with saturated aqueous ammonium chloride solution and once with brine, dried over anhydrous sodium sulfate and concentrated to give 0.85 g of the title compound; EI-MS, m/e (rel intensity): 234 (M+, 23), 136 (100), 109 (12), 91 (21).

المصدر