تفاعل #60658

معادلة التفاعل

tert-Butyl 4-(2-methoxy-2-oxoethylidene)piperidine-1-carboxylate

water

→

title compound

المردود 99.9%

tert-butyl 4-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate

المردود 99.9%

المذيبات

MeOH

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture was filtered through Celite
2. 2
   تركيزconcentrated

الإجراء التجريبي

tert-Butyl 4-(2-methoxy-2-oxoethylidene)piperidine-1-carboxylate (3.6 g, 14 mmol) and 10% Pd/C moistered with water (0.8 g) was mixed in MeOH (75 mL) and stirred under H2 (1 atm) for 4 h. The mixture was filtered through Celite and concentrated to give the title compound (3.6 g, 99%).

المصدر