تفاعل #6024

معادلة التفاعل

methyl 4-hydroxy-3-propenylbenzoate

potassium carbonate

allyl bromide

→

title compound

المردود 87.0%

methyl 3-(2-propen-1-yl)-4-(2-propen-1-yloxy)benzoate

المردود 87.0%

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture was filtered through Celite
2. 2
   غسيلthe filter cake was washed with more acetone and dichloromethane
3. 3
   أخرىAfter removing the solvents
4. 4
   workup.DISTILLATIONthe resulting oil was distilled under high vacuum

الإجراء التجريبي

A solution of 3.04 g (15.8 mmol) of methyl 4-hydroxy-3-propenylbenzoate (Example 42, Step B) was refluxed with anhydrous potassium carbonate (4.37 g, 2 equiv) and allyl bromide (3.5 mL, 2.5 equiv) in acetone overnight. The mixture was filtered through Celite and the filter cake was washed with more acetone and dichloromethane. After removing the solvents, the resulting oil was distilled under high vacuum to give 3.2 g (87%) of the title compound.

المصدر