تفاعل #6011

معادلة التفاعل

acetyl chloride

aluminum chloride

dimethylformamide

benzoselenazolinone

→

6-Acetylbenzoselenazolinone

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةAfter cooling
2. 2
   workup.STIRRINGthe mixture is homogenized
3. 3
   درجة الحرارةIt is heated to 70°-80° C. on an oil bath
4. 4
   workup.STIRRINGwith stirring
5. 5
   درجة الحرارةheating
6. 6
   درجة الحرارةis maintained at a temperature of 80°-90° C. for a time T of approximately 4 h 30 min
7. 7
   أخرىon crushed ice
8. 8
   أخرىdried
9. 9
   غسيلwashed with boiling cyclohexane
10. 10
    أخرىrecrystallized in toluene

الإجراء التجريبي

12 grams (0.09 mol) of aluminum chloride are introduced into a ground-necked flask. 3.1 cm3 (0.04 mol) of dimethylformamide are added dropwise with stirring. After cooling, two grams (0.01 mol) of benzoselenazolinone are added and the mixture is homogenized. It is heated to 70°-80° C. on an oil bath with stirring, and 0.01 to 0.012 mol of acetyl chloride is then added. heating is maintained at a temperature of 80°-90° C. for a time T of approximately 4 h 30 min. The mixture is hydrolyzed on crushed ice. The product is drained, dried, and washed with boiling cyclohexane and recrystallized in toluene.

المصدر