تفاعل #59975

معادلة التفاعل

( 4j )

2-(((4-(2-(8-ethyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)ethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

2-(8-methyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)ethanol

→

5-methyl-1H-benzimidazole-2-thiol

ظروف التفاعل

الإجراء التجريبي

The same procedure as in the steps (4f) to (4j) of Example 4 was repeated using 2-(8-methyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)ethanol obtained in the step (73b) above and 5-methyl-1H-benzimidazole-2-thiol obtained in the step (47a) to obtain the title compound (188 mg, total 12.4% yield) as a white solid.

المصدر