تفاعل #59974

معادلة التفاعل

( 4j )

2-(((4-(2-(8-ethyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)ethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

2-(8-methyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)ethanol

→

title compound

المردود 15.1%

2-(((3-methyl-4-(2-(8-methyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)ethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

المردود 15.1%

ظروف التفاعل

المعالجة

1. 1
   أخرىobtained in the step (73b) above

الإجراء التجريبي

The same procedure as in the steps (4f) to (4j) of Example 4 was repeated using 2-(8-methyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)ethanol obtained in the step (73b) above to obtain the title compound (298 mg, total 15.1% yield) as a white solid.

المصدر