تفاعل #5982

معادلة التفاعل

methyl 1-acetylamino-2-chloro6,7,8,9-tetrahydrodibenzofuran-4-carboxylate

→

methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate

ظروف التفاعل

المعالجة

1. 1
   استخلاصThe cooled residue is extracted with toluene
2. 2
   أخرىthe solvent evaporated to dryness
3. 3
   أخرىThe residue is crystallized from ethyl acetate/hexane

الإجراء التجريبي

A mixture of 1 g methyl 1-acetylamino-2-chloro6,7,8,9-tetrahydrodibenzofuran-4-carboxylate and 0.5 g of 5% palladium-charcoal is heated under nitrogen at 230° C. for 5 hours. The cooled residue is extracted with toluene and the solvent evaporated to dryness. The residue is crystallized from ethyl acetate/hexane to give methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate.

المصدر