تفاعل #596453

معادلة التفاعل

Tert-butyl 4-(4-fluorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate

→

colorless oil

المردود 95.2%

tert-butyl 4-(4-fluorophenyl)piperidine-1-carboxylate

المردود 95.2%

المذيبات

EtOH

ظروف التفاعل

المعالجة

1. 1
   أخرىThe resulting reaction liquid
2. 2
   ترشيحwas filtered
3. 3
   تركيزconcentrated under reduced pressure
4. 4
   أخرىdried under vacuum

الإجراء التجريبي

Tert-butyl 4-(4-fluorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate (48 mg, 0.173 mmol) was dissolved in EtOH (2 ml), followed by addition of Pd (10 wt % on activated carbon, 5 mg), and then the resulting liquid was stirred at room temperature under hydrogen stream for 2 hours. The resulting reaction liquid was filtered, concentrated under reduced pressure, and dried under vacuum, to obtain 46 mg of colorless oil (95%).

المصدر