تفاعل #595402

معادلة التفاعل

N-(3-(3,6-dibromo-9H-carbazol-9-yl)propyl)-2-nitro-N-phenylbenzenesulfonamide

cesium carbonate

benzenethiol

→

colorless oil

المردود 60.9%

N-(3-(3,6-dibromo-9H-carbazol-9-yl) propyl)aniline

المردود 60.9%

المذيبات

THF

ظروف التفاعل

المعالجة

1. 1
   أخرىTHF was removed under vacuum
2. 2
   أخرىthe residue was purified by silica gel chromatography

الإجراء التجريبي

N-(3-(3,6-dibromo-9H-carbazol-9-yl)propyl)-2-nitro-N-phenylbenzenesulfonamide (0.0378 g, 0.0588 mmol, 1 equiv), cesium carbonate (0.0574 g, 0.176 mmol, 3 equiv) and benzenethiol (0.0194 g, 0.176 mmol) were mixed in 1 mL anhydrous THF. The mixture was stirred at room temperature for 3 hours. THF was removed under vacuum and the residue was purified by silica gel chromatography using Hexanes/EtOAc to afford 0.0164 g colorless oil as product, yield 60.9%.

المصدر