تفاعل #595322

معادلة التفاعل

potassium 1-allylcyclopropane-1-sulfonate

thionyl chloride

→

crude product

1-allylcyclopropane-1-sulfonyl chloride

ظروف التفاعل

المعالجة

1. 1
   أخرىThe volatiles evaporated under reduced pressure
2. 2
   استخلاصthe residue extracted with CH2Cl2 (50 ml)
3. 3
   غسيلThe extract was washed with water
4. 4
   تجفيفdried (MgSO4)
5. 5
   أخرىevaporated

الإجراء التجريبي

A solution of potassium 1-allylcyclopropane-1-sulfonate (3.44 g, 17.2 mmol), thionyl chloride (10 ml) and DMF (5 drops) was refluxed at 60° C. for 16 h. The volatiles evaporated under reduced pressure and the residue extracted with CH2Cl2 (50 ml). The extract was washed with water, dried (MgSO4) and evaporated to obtain the crude product as yellow gummy oil which was washed with hexane and used in the next reaction without further purification (2.7 g, 15 mmol, 87%). 1HNMR (300 MHz, CDCl3): δ 5.728 (m, 1H), 5.191 (t, 2H), 2.9 (d, 2H), 0.756 (m, 2H), 0.322 (m, 2H).

المصدر