تفاعل #58863

معادلة التفاعل

K2CO3

pentynol

t-butyldiphenylsilylchloride

Et3N

→

t-butylpent-4-ynyloxy diphenyl silane

المردود 98.0%

المذيبات

CH2Cl2

ظروف التفاعل

المعالجة

1. 1
   استخلاصextracted with CH2Cl2
2. 2
   تجفيفThe combined extracts are dried over MgSO4
3. 3
   تركيزconcentrated in vacuo
4. 4
   ترشيحThe residue is purified by filtration on a silica pad

الإجراء التجريبي

A mixture of pentynol (8.0 g, 95 mmol), t-butyldiphenylsilylchloride (28 g, 114 mmol) and Et3N (14 g, 138 mmol) in CH2Cl2 is stirred at room temperature for 16 h, treated with 1M K2CO3 and extracted with CH2Cl2. The combined extracts are dried over MgSO4 and concentrated in vacuo. The residue is purified by filtration on a silica pad to obtain 30 g of t-butylpent-4-ynyloxy diphenyl silane (yield: 98%

المصدر