تفاعل #58676

معادلة التفاعل

1,3,5-benzenetricarboxylic acid trichloride

cyclooctylamine

LiCl

NMP

→

1,3,5-benzenetricarboxylic acid tris(cyclooctylamide)

المذيبات

pyridine

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe reaction mixture is heated to 75° C.
2. 2
   أخرىCustomary work-up (recrystallization from N,N-dimethylformamide)

الإجراء التجريبي

4.20 g (33 mmol) of cyclooctylamine and 0.1 g of dry LiCl are added under inert atmosphere to 70 ml of dry NMP and 15 ml of dry pyridine and cooled to 5° C. Then, 2.39 g (9 mmol) of 1,3,5-benzenetricarboxylic acid trichloride are added. The reaction mixture is heated to 75° C. and stirred. After 2 hours the reaction mixture is added to 300 ml of ice water. Customary work-up (recrystallization from N,N-dimethylformamide) gives 1,3,5-benzenetricarboxylic acid tris(cyclooctylamide).

المصدر