تفاعل #58463

ord-1144f5332b1843c28d484eec61caddb4

معادلة التفاعل

CC(C)(C)OC(=O)N1CCCCC1CC(=O)O
2-(RS)-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester
[Cl-].[NH4+]
ammonium chloride
→
CC(C)(C)OC(=O)N1CCCCC1CC(N)=O
title compound
المردود 46.2%
CC(C)(C)OC(=O)N1CCCCC1CC(N)=O
(RS)-2 Carbamoylmethyl-piperidine-1-carboxylic acid tert butyl ester
المردود 46.2%

المتفاعلات

CC(C)(C)OC(=O)N1CCCCC1CC(=O)O
2-(RS)-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester
[Cl-].[NH4+]
ammonium chloride

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound (0.92 g) wvas prepared from 2-(RS)-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (2.0 g) and ammonium chloride (0.86 g) according to the method of Example 97.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07423052B2uspto-grants-2008_09