تفاعل #58425
ord-d662b7b1e994447ab29f72792bedc7fd
معادلة التفاعل
(2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone
ethyl4-amino-1-piperidine carboxylate
→
title compound
4-[6-Amino-5-(5-fluoro-2-methoxy-4-chloro-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester
المتفاعلات
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone (Example 47) and ethyl4-amino-1-piperidine carboxylate (Aldrich 96%) using the procedure described in Step B. Example 6. HRMS, observed: 451.1545, Calcd for (M+H)+: 451.1543.