تفاعل #571365

معادلة التفاعل

2'-hydroxy[1,1':3',1"-terphenyl]-5'-yl thiocyanate

Triethyl phosphine

→

5'-mercapto[1,1':3',1"-terphenyl]-2'-ol

المذيبات

water

acetone

ظروف التفاعل

المعالجة

1. 1
   workup.WAITat room temperature for 2 hours
2. 2
   أخرىThe solvent was evaporated
3. 3
   أخرىthe product isolated by chromatography on silica

الإجراء التجريبي

2'-hydroxy[1,1':3',1"-terphenyl]-5'-yl thiocyanate (32.2 g, 0.106 mole) was dissolved in acetone (150 ml) and water (1.9 ml), stirred and cooled to -5° C. Triethyl phosphine (15.7 ml, 0.106 mole) was added dropwise over a period of 40 minutes. The reaction was stirred at 0° C. for 1 hour and then at room temperature for 2 hours. The solvent was evaporated and the product isolated by chromatography on silica.

المصدر