تفاعل #56901

ord-259a30fc5e5e4324970d143e2ce02bf7

معادلة التفاعل

CCOc1ccc(Cl)cc1-c1cc(Cl)nc(N)n1
4-chloro-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-2-ylamine
OB(O)c1cccc(Cl)c1Cl
2,3-dichlorophenyl boronic acid
Nc1nc(Cl)cc(Cl)n1
2-amino-4,6-dichloropyrimidine
Nc1nc(Cl)cc(-c2cccc(Cl)c2Cl)n1
4-Chloro-6-(2,3-dichloro-phenyl)-pyrimidin-2-ylamine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

4-Chloro-6-(2,3-dichloro-phenyl)-pyrimidin-2-ylamine was prepared according to the method described for 4-chloro-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-2-ylamine (Example 53) using 2,3-dichlorophenyl boronic acid and 2-amino-4,6-dichloropyrimidine.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07419984B2uspto-grants-2008_09