تفاعل #56880

معادلة التفاعل

4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine

4-amino-benzonitrile

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title compound

المردود 72.0%

4-[2-Amino-6-(5-bromo-2-methyl-phenyl)-pyrimidin-4-ylamino]-benzonitrile

المردود 72.0%

ظروف التفاعل

الإجراء التجريبي

Following the method described in Example 26, 4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine and 4-amino-benzonitrile provided the title compound (72% yield). 1H NMR (CD3OD) δ 2.40 (s, 3H, CH3), 6.38 (s, 1H, Ar), 7.39 (d, 1H, J=8.9 Hz, Ar), 7.68-7.69 (m, 2H, Ar), 7.78-7.80 (m, 2H, Ar), 8.07 (d, 2H, J=7.6 Hz, Ar).

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