تفاعل #565300

معادلة التفاعل

6-N-benzyloxycarbonyl-L-lysine

trifluoroacetic acid ethyl ester

→

2-N-Trifluoroacetyl-6-N-benzyloxycarbonyl-L-lysine

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىIt is evaporated to the dry state
2. 2
   أخرىthe residue is crystallized from diisopropyl ether

الإجراء التجريبي

100.0 g (356.7 mmol) of 6-N-benzyloxycarbonyl-L-lysine is dissolved in a mixture that consists of 1000 ml of trifluoroacetic acid ethyl ester and 500 ml of ethanol, and it is stirred for 24 hours at room temperature. It is evaporated to the dry state, and the residue is crystallized from diisopropyl ether.

المصدر