تفاعل #56518

معادلة التفاعل

9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate

hydroxylamine hydrochloride

sodium formate

→

9-Hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carbonitrile

المذيبات

formic acid

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةis refluxed for 30 hrs
2. 2
   أخرىThe product crystallize
3. 3
   درجة الحرارةon cooling
4. 4
   ترشيحis filtered
5. 5
   غسيلwashed with acetone

الإجراء التجريبي

A mixture of 9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate (1 mm), hydroxylamine hydrochloride (1.3 mm) and sodium formate (2 mm) is refluxed for 30 hrs. in formic acid (3 parts). The product crystallize on cooling, is filtered and washed with acetone. The dry crystals are light beige, m.p. 289°-92° C.

المصدر