تفاعل #564952

معادلة التفاعل

ethylenediamine

1-amino-5-bromo-2-nitronaphthalene

→

1-amino-5-cyano-2-nitronaphthalene

المردود 80.0%

المذيبات

water

dimethylformamide

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe reaction mixture was refluxed for 5 h
2. 2
   ترشيحthe precipitate was filtered off
3. 3
   غسيلwashed with water

الإجراء التجريبي

To a solution of 1,6 g (5,9 mmol) 1-amino-5-bromo-2-nitronaphthalene in 50 ml dimethylformamide was added 1,1 g (11,8 mmol) cuprous cyanide. The reaction mixture was refluxed for 5 h, and then poured into a solution of 2,5 ml ethylenediamine in 80 ml water. Stirring was continued for 15 min., and then the precipitate was filtered off and washed with water and boiling ethyl acetate to give 1,0 g (80%) 1-amino-5-cyano-2-nitronaphthalene.

المصدر