تفاعل #564942

معادلة التفاعل

1,2-diethoxalylamino-4-bromonaphthalene

→

6-bromo-2,3-dihydroxybenzo(f)quinoxaline

المردود 90.0%

المذيبات

hydrochloric acid

acetic acid

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas refluxed for 1,5 h
2. 2
   ترشيحthe precipitate was filtered off
3. 3
   أخرىThe crude product was recrystallized (dimethylformamide-water)

الإجراء التجريبي

A mixture of 2,0 g (4,6 mmol) 1,2-diethoxalylamino-4-bromonaphthalene in 50 ml 2N hydrochloric acid and 25 ml acetic acid was refluxed for 1,5 h. After cooling to 25° C., the precipitate was filtered off. The crude product was recrystallized (dimethylformamide-water) to give 1,2 g (90%) of pure 6-bromo-2,3-dihydroxybenzo(f)quinoxaline.

المصدر