تفاعل #56452

معادلة التفاعل

ethyl 4-nitro-benzamidoacetate

→

stated product

المردود 96.4%

Ethyl 4-amino-benzamidoacetate

المردود 96.4%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحthe catalyst is filtered off
2. 2
   أخرىthe filtrate is evaporated to dryness in vacuo
3. 3
   ترشيحthe product is filtered off

الإجراء التجريبي

17.6 g (0.07 mol) of ethyl 4-nitro-benzamidoacetate dissolved in 250 ml of ethanol are hydrogenated in the presence of a catalyst (2 g of palladium on charcoal); the catalyst is filtered off, the filtrate is evaporated to dryness in vacuo, the residue is taken up in 100 ml of diisopropyl ether and the product is filtered off. 15 g (87% yield) of the stated product are obtained. Melting point: 93°-94° C.

المصدر