تفاعل #563515

معادلة التفاعل

phenylmagnesium bromide

THF

phenylmagnesium bromide

1-Bromoadamantane

THF

→

title compound

1-Phenyladamantane

المذيبات

pentane

ظروف التفاعل

المعالجة

1. 1
   أخرىmaterials, and reacted as in Entry 1

الإجراء التجريبي

1-Bromoadamantane (215.4 mg, 1.0 mmol) and a THF solution (1.55 mL, 0.97 M, 1.50 mmol) of phenylmagnesium bromide were used as starting materials, and reacted as in Entry 1. Conditions: The THF solution of phenylmagnesium bromide was added dropwise at 40° C. over 3 hours. After silica gel column chromatography (pentane), the title compound was obtained as a white solid (0.173 g, yield 81%).

المصدر