تفاعل #56330

ord-41f134f4a569404e9f8323eace01fe5e

معادلة التفاعل

COc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2N)n1
2-amino-N-[(4-methoxy-6-methyl-2-pyrimidinyl)aminocarbonyl]benzenesulfonamide
Cl
HCl
→
COc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2N)n1.Cl
hydrochloride
COc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2N)n1.Cl
2-Amino-N-[(4-methoxy-6-methyl-2-pyrimidinyl)aminocarbonyl]benzenesulfonamide-Hydrochloride

المتفاعلات

COc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2N)n1
2-amino-N-[(4-methoxy-6-methyl-2-pyrimidinyl)aminocarbonyl]benzenesulfonamide
Cl
HCl

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    درجة الحرارةwas gently heated on a steam bath for 5 minutes
  2. 2
    أخرىThe resulting white suspension was evaporated in vacuo

الإجراء التجريبي

A suspension of 56 mg of 2-amino-N-[(4-methoxy-6-methyl-2-pyrimidinyl)aminocarbonyl]benzenesulfonamide in 5 ml of ethanolic HCl was gently heated on a steam bath for 5 minutes. The resulting white suspension was evaporated in vacuo to yield the hydrochloride m.p. 154-155 (dec.).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04225337uspto-grants-1980_09