تفاعل #56319

معادلة التفاعل

2-Methoxyaniline

sodium carbonate

2-Bromomethyl-4-methyl-5-ethyl-1,3-dioxolane

→

N-(4-methyl-5-ethyl-1,3-dioxolan-2-ylmethyl)-2-methoxyaniline

ظروف التفاعل

المعالجة

1. 1
   أخرىequipped with a mechanical stirrer
2. 2
   درجة الحرارةthermometer and reflux condenser
3. 3
   درجة الحرارةthe reaction mixture is heated
4. 4
   درجة الحرارةat reflux for a period of about 1 hour
5. 5
   ترشيحAfter this time the reaction mixture is filtered
6. 6
   workup.ADDITIONadditional sodium carbonate (5 grams) is added to the filtrate
7. 7
   workup.DISTILLATIONThe mixture is then distilled under reduced pressure

الإجراء التجريبي

2-Methoxyaniline (0.05 mole) and sodium carbonate (30 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2-Bromomethyl-4-methyl-5-ethyl-1,3-dioxolane (0.55 mole) is slowly added and the reaction mixture is heated at reflux for a period of about 1 hour. After this time the reaction mixture is filtered and additional sodium carbonate (5 grams) is added to the filtrate. The mixture is then distilled under reduced pressure to yield the desired product N-(4-methyl-5-ethyl-1,3-dioxolan-2-ylmethyl)-2-methoxyaniline.

المصدر