تفاعل #56138

ord-75216350ef6b4490a87c4ec3f64121cd

معادلة التفاعل

CCCOc1cc(C)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(C)c1C.[Cl-]
4-propoxy-2,3,6-trimethyl-benzyl-triphenyl-phosphonium chloride
CCOC(=O)C=C(C)C=CC=C(C)C=O
7-formyl-3-methyl-octa-2,4,6-trien-1-oic acid ethyl ester
→
CCCOc1cc(C)c(C=CC(C)=CC=CC(C)=CC(=O)OCC)c(C)c1C
9-(4-propoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester

المتفاعلات

CCCOc1cc(C)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(C)c1C.[Cl-]
4-propoxy-2,3,6-trimethyl-benzyl-triphenyl-phosphonium chloride
CCOC(=O)C=C(C)C=CC=C(C)C=O
7-formyl-3-methyl-octa-2,4,6-trien-1-oic acid ethyl ester

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

4-propoxy-2,3,6-trimethyl-benzyl-triphenyl-phosphonium chloride is condensed with 7-formyl-3-methyl-octa-2,4,6-trien-1-oic acid ethyl ester to produce 9-(4-propoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester which is converted by the procedure of Example 7 to 9-(4-propoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid, m.p.: 200°-201° C.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04224244uspto-grants-1980_09