تفاعل #55957

معادلة التفاعل

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene

sodium acetate

formamide

propionic anhydride

→

2-cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene

المردود 83.5%

المذيبات

n-butyl acetate

—

petroleum ether

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةare heated
2. 2
   درجة الحرارةThe temperature is maintained for 30 minutes
3. 3
   أخرىwhen reaction
4. 4
   درجة الحرارةThe mixture is cooled to room temperature
5. 5
   أخرىThe precipitate is collected
6. 6
   غسيلwashed with petroleum ether (100 parts)
7. 7
   أخرىdried

الإجراء التجريبي

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene (2.4 parts), copper (I) iodide (0.95 parts), anhydrous sodium acetate (1.2 parts), formamide (1.8 parts), propionic anhydride (2.6 parts) and n-butyl acetate (44 parts) are mixed together are heated, with stirring, to 110° C. during 15 minutes. The temperature is maintained for 30 minutes when reaction is adjudged complete by thin layer chromatography. The mixture is cooled to room temperature and poured into petroleum ether (boiling range 60-80° C.) (400 parts). The precipitate is collected, washed with petroleum ether (100 parts) and dried. 2-cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene is obtained in 83.5% yield.

المصدر