تفاعل #55771

معادلة التفاعل

2-mercaptoimidazole

3-aminopropanol

hydrobromic acid

→

2-(3-aminopropylthio)imidazole dihydrobromide

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةunder reflux for 25 hours
2. 2
   أخرىThe reaction mixture was evaporated to dryness
3. 3
   أخرىthe oily residual solid recrystallised twice from ethanol/ether

الإجراء التجريبي

A solution of 2-mercaptoimidazole (2 g.) and 3-aminopropanol (1.14 ml.) in hydrobromic acid (48%, 25 ml.) was heated under reflux for 25 hours. The reaction mixture was evaporated to dryness and the oily residual solid recrystallised twice from ethanol/ether to give 2-(3-aminopropylthio)imidazole dihydrobromide (3.55 g.), m.p. 160°-162°.

المصدر