تفاعل #554599

معادلة التفاعل

boron boron tribromide

water

2-methoxytriphenylene

→

2-hydroxytriphenylene

المردود 95.1%

المذيبات

methylene chloride

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwhile increasing temperature of the reaction solution to room temperature
2. 2
   ترشيحfollowed by filtration
3. 3
   غسيلThe resulting solid was washed with water and methanol

الإجراء التجريبي

Under an argon atmosphere, 13.9 g of 2-methoxytriphenylene was placed in a flask, and 300 mL of methylene chloride was added. The reaction solution was cooled to −78° C., and 54 mL of a solution of 1M boron boron tribromide in methylene chloride was dropwise added thereto. The reaction solution was stirred for 5 hours while increasing temperature of the reaction solution to room temperature. 100 mL of water was added to the reaction solution, followed by filtration. The resulting solid was washed with water and methanol to obtain 12.5 g (yield: 95%) of 2-hydroxytriphenylene.

المصدر