تفاعل #554567

معادلة التفاعل

Phosphorus oxychloride

dimethylaniline

phenanthridine

→

9-chlorophenanthridine

المردود 96.0%

المذيبات

H2O

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةby refluxing for 3 hours
2. 2
   استخلاصthe obtained solid was extracted with chloroform
3. 3
   تجفيفby drying with sodium sulfate
4. 4
   ترشيحAfter filtration
5. 5
   أخرىthe filtrate was evaporated to dryness under reduced pressure
6. 6
   أخرىThe obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%)

الإجراء التجريبي

Phosphorus oxychloride (15 ml) and dimethylaniline (0.63 ml) were added to phenanthridine (2.0 g), followed by refluxing for 3 hours. The solution was poured into H2O to generate a solid, and the obtained solid was extracted with chloroform, followed by drying with sodium sulfate. After filtration, the filtrate was evaporated to dryness under reduced pressure. The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%).

المصدر