تفاعل #552496

معادلة التفاعل

potassium nitrate

3-ethoxalylamino-1,8-naphthalenedicarboxylic anhydride

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title compound

المردود 77.0%

3-Ethoxalylamino-4-nitro-1,8-naphthalenedicarboxylic anhydride

المردود 77.0%

المذيبات

sulfuric acid

ظروف التفاعل

المعالجة

1. 1
   أخرىThe separated yellow solid was isolated by filtration
2. 2
   غسيلwashed with water, ethanol and ether

الإجراء التجريبي

Powdered potassium nitrate (0.51 g, 5 mmol) was added to a stirred solution of 3-ethoxalylamino-1,8-naphthalenedicarboxylic anhydride (1.57 g, 5 mmol) in 15 ml of conc. sulfuric acid at 0° C. Stirring was continued for 2 h at the same temperature, then the reaction mixture was poured into 150 ml of ice-water. The separated yellow solid was isolated by filtration and washed with water, ethanol and ether. Trituration with a small amount of ethyl acetate afforded 1.38 g (77%) of the title compound. M.p. 221°-222° C.; 1H-NMR (CDCl3 +DMSO-d6): 1.43 (t,J=7Hz, 3H, CH3), 4.37 (q,J=7Hz, 2H, CH2), 7.70-8.60 (m, 3H, ArH), 8.82 (s, 1H, H-2), 11.3 (broad s, 1H, NH).

المصدر