تفاعل #5505

معادلة التفاعل

Diethyl 2-t-butoxycarbonylamino-13-benzyloxycarbonyl-1,14-tetradecanedicarboxylate

→

diethyl 2-t-butoxycarbonylamino-13-carboxy-1,14-tetradecanedicarboxylate

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe product is then filtered through a pad of Celite
2. 2
   أخرىthe solvent is evaporated

الإجراء التجريبي

Diethyl 2-t-butoxycarbonylamino-13-benzyloxycarbonyl-1,14-tetradecanedicarboxylate (5.0 g, 8.87 mmol) is dissolved in ethyl acetate (150.0 mL), and 10% Pd-C (2.6 g) is added. The reaction flask is put under an atmosphere of hydrogen and stirred for 2 hours. The product is then filtered through a pad of Celite, and the solvent is evaporated to give diethyl 2-t-butoxycarbonylamino-13-carboxy-1,14-tetradecanedicarboxylate.

المصدر