تفاعل #54966

معادلة التفاعل

sodium p-toluenesulphinate

triethylamine

water

→

p-tolylmethylsulphone

المردود 81.1%

المذيبات

dimethyl methanephosphonate

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةthe mixture is heated in the course of 45 minutes to 167° C
2. 2
   workup.WAITstired for 1 hour
3. 3
   ترشيحThe precipitated crystalline product is collected by filtration
4. 4
   غسيلwashed with 350 ml of water
5. 5
   أخرىThe residue is dried at 25 torr and 50° C.

الإجراء التجريبي

A suspension of 22.7 g of sodium p-toluenesulphinate in 50 ml of dimethyl methanephosphonate is treated with 12.6 g of triethylamine and the mixture is heated in the course of 45 minutes to 167° C. The temperature is raised further to 171° C. and kept thereat for a further 30 minutes. The cooled solution is poured into 700 ml of water and stired for 1 hour. The precipitated crystalline product is collected by filtration and washed with 350 ml of water. The residue is dried at 25 torr and 50° C., affording 17.2 g (80.9% of theory) of p-tolylmethylsulphone of the formula ##STR14## with a melting point of 85°-96° C. and a purity of 95.8%.

المصدر