تفاعل #54891

معادلة التفاعل

4-(4-acetyl-8-hydroxytridecyl)benzoic acid

acetic anhydride

→

crude product

4-(4-Acetyl-8-acetoxytridecyl)benzoic Acid

المذيبات

ethyl ether

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe mixture is then cooled
2. 2
   workup.DISSOLUTIONdissolved in 80 ml
3. 3
   استخلاصThe solution is extracted with an ice-cold solution of 8 g
4. 4
   أخرىThe basic solution is separated
5. 5
   غسيلwashed with water
6. 6
   تجفيفdried over sodium sulfate
7. 7
   أخرىThe ether is evaporated

الإجراء التجريبي

A mixture of 4-(4-acetyl-8-hydroxytridecyl)benzoic acid (9.0 g., 0.025 mole) and acetic anhydride (6.1 g., 0.06 mole) is heated at 60° C. for 18 hours. The mixture is then cooled and dissolved in 80 ml. ethyl ether. The solution is extracted with an ice-cold solution of 8 g. sodium hydroxide in 150 ml. water. The basic solution is separated and acidified with concentrated hydrochloric acid. The oily acid which separates is taken up in ether, washed with water, and dried over sodium sulfate. The ether is evaporated to leave the oily crude product.

المصدر