تفاعل #54507

معادلة التفاعل

ethyl 4-(2-methylphenyl)-3-oxobutanoate

sodium methoxide

1-bromododecane

potassium iodide

→

ethyl 2-[(2-methylphenyl)acetyl]tetradecanoate

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe mixture was evaporated to a small volume
2. 2
   workup.ADDITIONdiluted with 100 parts water
3. 3
   استخلاصextracted with ether
4. 4
   استخلاصThe ether extract
5. 5
   غسيلwas washed with saturated sodium bicarbonate, saturated sodium chloride solution
6. 6
   تجفيفdried over magnesium sulfate
7. 7
   أخرىEvaporation of the ether

الإجراء التجريبي

Three parts of ethyl 4-(2-methylphenyl)-3-oxobutanoate, 1 part of sodium methoxide, 4.6 parts of 1-bromododecane, 0.5 parts of potassium iodide and 50 parts of absolute ethanol were refluxed together for 4 hours and then stirred 18 hours at room temperature. The mixture was evaporated to a small volume, diluted with 100 parts water and extracted with ether. The ether extract was washed with saturated sodium bicarbonate, saturated sodium chloride solution and dried over magnesium sulfate. Evaporation of the ether gave 6 parts of crude ethyl 2-[(2-methylphenyl)acetyl]tetradecanoate as an oil which was not further purified.

المصدر