تفاعل #54397

معادلة التفاعل

4,4-dibromo-3-methyl-1-(4-sulfophenyl)-2-pyrazolin-5-one

2-hydrazinopyridine

HCl

→

3-Methyl-4-(2-pyridylazo)-1-(4-sulfophenyl)-2-pyrazolin-5-one

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe mixture was heated on the steam bath a total of six hours
2. 2
   درجة الحرارةAfter a few minutes of heating
3. 3
   درجة الحرارةThe mixture was cooled somewhat
4. 4
   أخرىthe orange solid was isolated by suction filtration
5. 5
   غسيلAfter washing once with tetrahydrofuran, twice with ether
6. 6
   أخرىdrying

الإجراء التجريبي

41.0 g (0.10 mole) of 4,4-dibromo-3-methyl-1-(4-sulfophenyl)-2-pyrazolin-5-one, which can be prepared according to the method of Machiele, U.S. Pat. No. 3,952,009 (Example 1), and 16.0 g (0.15 mole) of 2-hydrazinopyridine were combined in 180 ml of water. The mixture was heated on the steam bath a total of six hours. After a few minutes of heating, the solution goes to a very thick slurry. The mixture was cooled somewhat, 10 ml of concentrated HCl were added, and the orange solid was isolated by suction filtration. After washing once with tetrahydrofuran, twice with ether, and drying, the yield of dye was 17.8 g (50 percent).

المصدر