تفاعل #54394

معادلة التفاعل

3-diallylsulphamoyl-1,2,4-triazole

diethylcarbamoyl chloride

triethylamine

→

1-diethylcarbamoyl-3-diallylsulphamoyl-1,2,4-triazole

المذيبات

tetrahydrofuran

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONA mixture of 6.9 g
2. 2
   أخرىThe cooled reaction mixture
3. 3
   ترشيحwas filtered
4. 4
   أخرىto remove triethylamine hydrochloride
5. 5
   أخرىthe filtrate was evaporated
6. 6
   أخرىto remove solvent
7. 7
   أخرىThe solid residue was recrystallized from petroleum ether, b.p. 60°-80° C.

الإجراء التجريبي

A mixture of 6.9 g. 3-diallylsulphamoyl-1,2,4-triazole, 4.5 g. diethylcarbamoyl chloride, 6ml. triethylamine and 25 ml. dry tetrahydrofuran was refluxed under anhydrous conditions for 1.5 hours. The cooled reaction mixture was filtered to remove triethylamine hydrochloride and the filtrate was evaporated to remove solvent. The solid residue was recrystallized from petroleum ether, b.p. 60°-80° C., to give 1-diethylcarbamoyl-3-diallylsulphamoyl-1,2,4-triazole, m.p. 49°-51° C. Elemental analysis satisfactory.

المصدر