تفاعل #54324

معادلة التفاعل

potassium

maleic anhydride

4-anilinophenol

4-anilinophenol

hydrochloric acid

potassium

→

4-Anilinophenyl hydrogen maleate

المذيبات

potassium tert.butoxide

water

tert.butyl alcohol

ظروف التفاعل

المعالجة

1. 1
   أخرىwas prepared
2. 2
   أخرىprepared
3. 3
   أخرىThe organic layer was separated by extraction with benzene
4. 4
   غسيلThe extract was washed twice with water
5. 5
   أخرىto evaporate
6. 6
   أخرىThe residue was recrystallized twice from benzene yielding 1.3 grams of product which melted at 139°-142° C.

الإجراء التجريبي

4-Anilinophenyl hydrogen maleate was prepared by adding 10 grams of maleic anhydride to a solution of the potassium salt of 4-anilinophenol which was prepared by dissolving 18.5 grams of 4-anilinophenol in a solution of potassium tert.butoxide prepared by reacting 3.9 grams of potassium with 75 milliliters of tert.butyl alcohol. The reaction mixture was stirred for two hours at 65°-70° C. and was then poured into a solution of 12 milliliters of concentrated hydrochloric acid in 138 milliliters of water. The organic layer was separated by extraction with benzene. The extract was washed twice with water and then allowed to evaporate. The residue was recrystallized twice from benzene yielding 1.3 grams of product which melted at 139°-142° C.

المصدر