تفاعل #54203

معادلة التفاعل

sodium hydroxide

2-bromofuran-5-aldehyde

THF

1-amino-2-oxo-imidazolidine hydrochloride

→

1-(5-bromofurylideneamino)-2-oxo-imidazolidine

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe precipitate is filtered off
2. 2
   غسيلwashed with water
3. 3
   أخرىrecrystallised from methanol

الإجراء التجريبي

33.5 pts. by wt. of 2-bromofuran-5-aldehyde, dissolved in 100 pts. by vol. of THF, are added to a solution of 1-amino-2-oxo-imidazolidine hydrochloride in 350 pts. by vol. of water, which has been adjusted to pH 5 with sodium hydroxide solution, and the mixture is stirred overnight. The precipitate is filtered off, washed with water and recrystallised from methanol. 30.0 pts. by wt. of 1-(5-bromofurylideneamino)-2-oxo-imidazolidine of dec. pt. 153°-158° C. are obtained.

المصدر