تفاعل #54151

معادلة التفاعل

2-hydroxy-4-methoxybenzaldehyde

ethyl acetoacetate

→

3-acetyl-7-methoxycoumarin

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas warmed on a hot plate until solution
2. 2
   درجة الحرارةto be heated gently
3. 3
   workup.WAITAfter several minutes the reaction mixture solidified
4. 4
   درجة الحرارةAfter cooling
5. 5
   أخرىthe product was recrystallized from a mixture of alcohol and acetonitrile

الإجراء التجريبي

A mixture of 15.2 g 2-hydroxy-4-methoxybenzaldehyde and 13.5 g ethyl acetoacetate was warmed on a hot plate until solution was attained. Thirty drops of piperidine were added and the reaction mixture continued to be heated gently. After several minutes the reaction mixture solidified. After cooling, the product was recrystallized from a mixture of alcohol and acetonitrile. Yield 20 g.

المصدر