تفاعل #54146

معادلة التفاعل

ethyl 3-amino-2-(4-chlorophenylcarbamoyl)crotonate

triethyl orthoacetate

triethyl orthoformate

→

Ethyl 1-(4-Chlorophenyl)-1,6-dihydro-2,4-dimethyl-6-oxopyrimidine-5-carboxylate

المردود 42.0%

ظروف التفاعل

الإجراء التجريبي

This compound is prepared in 42% yield from ethyl 3-amino-2-(4-chlorophenylcarbamoyl)crotonate in a manner analogous to Example 1 substituting triethyl orthoacetate for triethyl orthoformate.

المصدر