تفاعل #536923

معادلة التفاعل

1b

3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]propionic acid methyl ester

N-(4-cyano-phenyl)-glycine

CDI

→

3-({3-[2-(4-Cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-phenylamino)-propionic acid methyl ester

المذيبات

THF

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter completion of the reaction the mixture
2. 2
   أخرىwas evaporated to dryness
3. 3
   أخرىthe crude product was used without further purification

الإجراء التجريبي

The product of 1b (23.2 mmol) and N-(4-cyano-phenyl)-glycine (23.2 mmol) were coupled with CDI (23.2 mmol) in dry THF at room temperature. After completion of the reaction the mixture was evaporated to dryness and the crude product was used without further purification.

المصدر