تفاعل #531800

معادلة التفاعل

coronene

succinic anhydride

aluminum chloride

→

yellow-green solid

المردود 88.4%

γ-oxo-4-(coronen-1-yl)butanoic acid

المردود 88.4%

المذيبات

nitrobenzene

ظروف التفاعل

المعالجة

1. 1
   أخرىThe substance obtained here
2. 2
   أخرىwas immersed in an ice bath
3. 3
   أخرىthe reaction container was removed from the ice bath
4. 4
   workup.ADDITION10 ml of cooled 2M hydrochloric acid was added
5. 5
   workup.WAITfollowed by 10-minute
6. 6
   workup.STIRRINGstirring
7. 7
   درجة الحرارةThe substance was cooled slowly down to room temperature
8. 8
   أخرىto precipitate a solid substance
9. 9
   ترشيحThe solid substance was collected by filtration
10. 10
    workup.ADDITIONThis solid substance was dispersed in 20 ml of xylene
11. 11
    درجة الحرارةwas heated to 140° C
12. 12
    workup.DISSOLUTIONIn this manner, the solid substance was dissolved
13. 13
    درجة الحرارةThe substance was then cooled slowly back to room temperature
14. 14
    أخرىto precipitate a solid substance
15. 15
    أخرىThe solid substance obtained here
16. 16
    ترشيحwas collected by filtration
17. 17
    أخرىwas dried under reduced pressure

الإجراء التجريبي

The coronene 81 (0.699 g, 2.33 mmol) and 0.514 g (5.14 mmol) of succinic anhydride were put into a 100-ml two-inlet flask, and a nitrogen substitution was performed. The substance obtained here was immersed in an ice bath. After 2.80 g (21.0 mmol) of aluminum chloride dispersed in 20 ml of nitrobenzene was slowly dripped onto the substance, the reaction container was removed from the ice bath, and the substance was stirred at room temperature for 5 hours. After the reaction was completed, 10 ml of cooled 2M hydrochloric acid was added, followed by 10-minute stirring. The substance was cooled slowly down to room temperature, to precipitate a solid substance. The solid substance was collected by filtration. This solid substance was dispersed in 20 ml of xylene, and was heated to 140° C. In this manner, the solid substance was dissolved. The substance was then cooled slowly back to room temperature, to precipitate a solid substance. The solid substance obtained here was collected by filtration, and was dried under reduced pressure, to obtain 0.825 g of the yellow-green solid substance 82.

المصدر